1 Result for "

HFB200901

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HFB200901" in MCE Product Catalog:

HFB200901
HFB200901
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Cat. No.: HY-P992366

Target:  

Galectin Tim3

Research Areas:  

Cancer

HFB200901 is a galectin LGALS9 inhibitor and immunostimulant that can be used in studies related to pancreatic adenocarcinoma, pancreatic intraepithelial neoplasia, KRAS G12C-mutant colon cancer, and prostate cancer. HFB200901 disrupts the LGALS9/TIM-3 axis, while blocking the internalization and vacuolization of recombinant LGALS9. HFB200901 reduces the proportion of regulatory T cells (Treg) and enhances dendritic cell activation, thereby inducing polyfunctional and memory CD8 + T cell responses. HFB200901 inhibits the progression of pancreatic neoplastic lesions and effectively improves the efficacy of PSMA-based vaccination .
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