1 Result for "

HIV-like particles

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HIV-like particles" in MCE Product Catalog:

Cat. No.: HY-183376
CAS No.: 126103-94-4
Target:  

HIV Protease

Research Areas:  

Infection

U 81749 is a competitive, reversible HIV-1 protease inhibitor with a Ki value of 70 nM. U 81749 inhibits HIV-1 protease within HIV-like particles, blocks the processing of the HIV-1 gag polyprotein p55 into the mature structural proteins p24 and p17, and thereby prevents viral maturation. U 81749 reduces HIV p24 and HIV RNA levels in acutely infected human lymphocytes, and shows no toxicity to lymphocyte proliferation at effective concentrations. U 81749 can be used in studies related to HIV-1 infection .
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