1 Result for "

HMR3480

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HMR3480" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-19676
CAS No.: 192755-52-5
Synonyms: VX-740; HMR 3480
Target:  

Caspase

Research Areas:  

Inflammation/Immunology

Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active interleukin-1β converting enzyme (ICE, caspase 1) inhibitor with a Ki of 1.4 nM. Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment .
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