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HOMER1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (2) Autophagy (2) Calcium Channel (2) CaMK (2) CRAC Channel (2) Na+/Ca2+ Exchanger (2) Small Interfering RNA (siRNA) (3) TRP Channel (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (2) Neurological Disease (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100001

SKF-96365 (hydrochloride) 25+ Cited Publications	TRP Channel CRAC Channel Autophagy CaMK Akt Apoptosis Na+/Ca2+ Exchanger Calcium Channel	Neurological Disease Inflammation/Immunology Cancer
SKF-96365 hydrochloride is a TRPC channel antagonist and store-operated calcium entry (SOCE) inhibitor. SKF-96365 hydrochloride reduces calcium ion influx by inhibiting the activity and expression of TRPC6, *STIM1* and *Orai1. SKF-96365 hydrochloride inhibits voltage-gated sodium current (cardiac I_Na/NaV1.5) and slows myocardial conduction. SKF-96365 hydrochloride inhibits phosphorylation/activation of CaMKIIγ* and suppresses the downstream AKT signaling pathway. SKF-96365 hydrochloride induces G₂/M phase cell cycle arrest, apoptosis and cytoprotective autophagy in colorectal cancer cells. SKF-96365 hydrochloride alleviates allergic rhinitis symptoms by reducing inflammatory cytokine levels. SKF-96365 hydrochloride reduces intracellular calcium overload, inhibits *Homer1* expression, prevents nuclear damage and suppresses apoptosis. SKF-96365 hydrochloride inhibits the growth of colorectal cancer xenografts in nude mice . SKF-96365 hydrochloride is applicable to research related to allergic rhinitis, colorectal cancer, Parkinson's disease, persistent spontaneous nociception and hyperalgesia ^[1] .

HY-RS21139

Homer1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Homer1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Homer1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Homer1 Mouse Pre-designed siRNA Set A Homer1 Mouse Pre-designed siRNA Set A

HY-125942

SKF-96365 25+ Cited Publications	CRAC Channel TRP Channel CaMK Akt Apoptosis Autophagy Na+/Ca2+ Exchanger Calcium Channel	Neurological Disease Inflammation/Immunology Cancer
SKF-96365 is a TRPC channel antagonist and store-operated calcium entry (SOCE) inhibitor. SKF-96365 reduces calcium ion influx by inhibiting the activity and expression of TRPC6, *STIM1* and *Orai1. SKF-96365 inhibits voltage-gated sodium current (cardiac I_Na/NaV1.5) and slows myocardial conduction. SKF-96365 inhibits phosphorylation/activation of CaMKIIγ* and suppresses the downstream AKT signaling pathway. SKF-96365 induces G₂/M phase cell cycle arrest, apoptosis and cytoprotective autophagy in colorectal cancer cells. SKF-96365 alleviates allergic rhinitis symptoms by reducing inflammatory cytokine levels. SKF-96365 reduces intracellular calcium overload, inhibits *Homer1* expression, prevents nuclear damage and suppresses apoptosis. SKF-96365 inhibits the growth of colorectal cancer xenografts in nude mice . SKF-96365 is applicable to research related to allergic rhinitis, colorectal cancer, Parkinson's disease, persistent spontaneous nociception and hyperalgesia ^[1] .

HY-RS06283

HOMER1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HOMER1 Human Pre-designed siRNA Set A contains three designed siRNAs for HOMER1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HOMER1 Human Pre-designed siRNA Set A HOMER1 Human Pre-designed siRNA Set A

HY-RS27657

Homer1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Homer1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Homer1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Homer1 Rat Pre-designed siRNA Set A Homer1 Rat Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705527

	Homer1 Protein, Human (His) HOME1_HUMAN; HOMER ; HOMER 1A; HOMER 1B ; HOMER 1C; HOMER homolog 1 (Drosophila); HOMER homolog 1; HOMER protein homolog 1; HOMER scaffolding protein 1; HOMER; Drosophila; homolog of; 1; HOMER; neuronal immediate early gene; 1 ; HOMER-1; HOMER1; HOMER1A; HOMER1B; HOMER1C; SYN47 ; Ves 1	Human	E. coli

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Host:	Rabbit (3)
Reactivity:	Rat (3) Mouse (3)
Application:	IHC-P (1) IP (2) IHC-F (1) WB (3)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83290

	Homer1 Antibody (YA3035) HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER1C	WB, IP	Mouse, Rat
	Homer1 Antibody (YA3035) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Homer1.

HY-P83290A

	Homer1 Antibody (YA3035)(PBS only) HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER1C	WB, IP	Mouse, Rat
	Homer1 Antibody (YA3035) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Homer1.

HY-P86909

	Homer1 Antibody (YA6602) HOME1_HUMAN antibody; HOMER antibody; HOMER 1A antibody; HOMER 1B antibody; HOMER 1C antibody; HOMER homolog 1 (Drosophila) antibody; HOMER homolog 1 antibody; HOMER protein homolog 1 antibody; HOMER scaffolding protein 1 antibody; HOMER, Drosophila, homolog of, 1 antibody; HOME1_HUMAN antibody; HOMER antibody; HOMER 1A antibody; HOMER 1B antibody; HOMER 1C antibody; HOMER homolog 1 (Drosophila) antibody; HOMER homolog 1 antibody; HOMER protein homolog 1 antibody; HOMER scaffolding protein 1 antibody; HOMER, Drosophila, homolog of, 1 antibody; HOMER, neuronal immediate early gene, 1 antibody; HOMER-1 antibody; HOMER1 antibody; HOMER1A antibody; HOMER1B antibody; HOMER1C antibody; SYN47 antibody; Ves 1 antibody;	WB, IHC-P, IHC-F	Mouse, Rat
	Homer1 Antibody (YA6602) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Homer1.

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Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Homer1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Homer1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Homer1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HOMER1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
HOMER1 Human Pre-designed siRNA Set A contains three designed siRNAs for HOMER1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Homer1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Homer1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Homer1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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