1 Result for "

HSP76

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HSP76" in MCE Product Catalog:

Cat. No.: HY-181147
Target:  

PROTACs HSP

Research Areas:  

Cancer

PROTAC HSP70 Degrader-1 (compound C4) is a cytosolic HSP70 PROTAC degrader that can engage CRBN to form a ternary complex. PROTAC HSP70 Degrader-1 mediates ubiquitination and proteasomal degradation of cytosolic HSP70. PROTAC HSP70 Degrader-1 exhibits cytotoxic activity against cancer cells, suppressing tumor cell proliferation and inducing apoptosis in combination with DTHIB. PROTAC HSP70 Degrader-1 can be used for the research of colon cancer and leukemia .
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