4 Results for "

HTC116

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HTC116" in MCE Product Catalog:

Cat. No.: HY-144650
CAS No.: 2361009-68-7
Purity:  98.09%
Target:  

Apoptosis HSP

Research Areas:  

Cancer

Hsp90-Cdc37-IN-3 (Compound 9) is a novel celastrol−imidazole derivative with anticancer activity. Hsp90-Cdc37-IN-3 inhibits Hsp90Cdc37 by covalent-binding, and induces apoptosis .
loading...
    loading...
Cat. No.: HY-172733S
CAS No.: 3052146-54-7
PRMT5-MTA-IN-3-d3 (compound P22) is the deuterium labeled PRMT5-MTA-IN-3 (HY-172733). PRMT5-MTA-IN-3-d3 is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d3 has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC50 values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d3 has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer (NSCLC), pancreatic cancer .
loading...
    loading...
Cat. No.: HY-163401
CAS No.: 640263-95-2
Target:  

Epoxide Hydrolase

Research Areas:  

Cancer

Epoxykynin is a potent epoxide hydrolase (sEH) inhibitor .
loading...
    loading...
Cat. No.: HY-173314
Target:  

EGFR Apoptosis

Research Areas:  

Cancer

EGFR-IN-155 (compound 13a) is an EGFR inhibitor with IC50 values of 0.14 nM and 0.18 nM against EGFR TK and EGFR L858R, respectively. EGFR-IN-155 inhibits tumor growth, causes a cell cycle arrest at S phase, and and induces cell apoptosis .
loading...
    loading...