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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
HaloPROTAC-E
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "HaloPROTAC-E" in MCE Product Catalog:
1
1 Cited Publications
HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy.
Referencia número: HY-W613607
No. CAS: 1355955-95-1
Target:
Áreas de investigación:
HO-PEG3-(CH2)6-Cl is a PROTAC linker that can be used to synthesize HaloPROTAC-E (HY-145752) .
Referencia número: HY-W260045
No. CAS: 22692-46-2
Áreas de investigación:
1-Chloro-6-methoxyhexane is a target protein ligand for PROTAC. 1-Chloro-6-methoxyhexane can be used to synthesize the PROTAC HaloPROTAC-E (HY-145752).
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
