1 Result for "

His122

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "His122" in MCE Product Catalog:

Cat. No.: HY-B0967
CAS No.: 131-69-1
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Phthalylsulfacetamide is an orally active sulfonamide antibiotic and New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 15.4 μM. Phthalylsulfacetamide stably binds to the active hydrolysis center of NDM-1, interacts with Zn2+, and interacts with key amino acid residues Val73 and His122 to inhibit enzyme activity. Phthalylsulfacetamide can be used for the research of Escherichia coli infection .
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