2 Results for "

His28

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "His28" in MCE Product Catalog:

Cat. No.: HY-P5184
CAS No.: 651782-02-4
Synonyms: HNTX-IV
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif .
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Cat. No.: HY-187373
CAS No.: 1808751-57-6
Research Areas:  

Cancer

DDAH1-IN-3 is a DDAH1 inhibitor with a human IC50 of 176 μM. DDAH1-IN-3 binds to the DDAH1 active site, forms binding interactions that remodel the binding pocket, and functionally inhibits the enzyme. DDAH1-IN-3 suppresses vasculogenic mimicry in triple-negative breast cancer cells. DDAH1-IN-3 can be used for the research of triple-negative breast cancer .
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