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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Hsp70-interacting
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Hsp70-interacting" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-18619
CAS No.: 36341-25-0
Target:
Research Areas:
YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness .
1
1 Cited Publications
Cat. No.: HY-P701386
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HspBP1; Hsp70-interacting Protein 2; HspA (Hsp70) Binding Protein 1; Hsp70-interacting Protein 1; FES1; Hsp70-Binding Protein 2; HspA (Heat Shock 70kDa) Binding Protein, Cytoplasmic Cochaperone 1; HspBP2; Heat Shock Protein-Binding Protein 1; HspBP1; Hsp7
Target:
Research Areas:
GNA002 is a highly potent, specific and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor with an IC50 of 1.1 μM. GNA002 can specifically and covalently bind to Cys668 within the EZH2-SET domain, triggering EZH2 degradation through COOH terminus of Hsp70-interacting protein (CHIP)-mediated ubiquitination. GNA002 efficiently reduces EZH2-mediated H3K27 trimethylation, reactivates polycomb repressor complex 2 (PRC2)-silenced tumor suppressor genes .
Cat. No.: HY-P701387
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HspBP1; Hsp70-interacting Protein 2; HspA (Hsp70) Binding Protein 1; Hsp70-interacting Protein 1; FES1; Hsp70-Binding Protein 2; HspA (Heat Shock 70kDa) Binding Protein, Cytoplasmic Cochaperone 1; HspBP2; Heat Shock Protein-Binding Protein 1; HspBP1; Hsp7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
