1 Result for "

HuFBPase

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HuFBPase" in MCE Product Catalog:

Cat. No.: HY-182346
Target:  

FBPase

Research Areas:  

Metabolic Disease

FBPase-IN-7 is a fructose-1,6-bisphosphatase (FBPase) inhibitor with an IC50 of 0.75 μM. FBPase-IN-7 binds to a cryptic allosteric pocket of FBPase, induces conformational rearrangement of key residues, forms a hydrogen-bond network, and disrupts substrate catalysis. FBPase-IN-7 confirms cellular stabilizes HuFBPase in hepatic cells. FBPase-IN-7 has hypoglycemic activity. FBPase-IN-7 can be used for the research of type 2 diabetes .
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