49 Results for "

IL36

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "IL36" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P70702
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL-36 alpha; IL-36α; Interleukin-36 Alpha; FIL1 EpsILon; Interleukin-1 EpsILon; IL-1 EpsILon; Interleukin-1 FamILy Member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6
Species:  
Source:  
1
1 Cited Publications
Cat. No.: HY-P77007
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL-36RA; Interleukin-36 Receptor Antagonist Protein; IL-1RP3; IL-1F5; IL-1L1; FIL1D; IL1HY1
Species:  
Source:  
Cat. No.: HY-P99396
CAS No.: 2097104-58-8
Synonyms: BI 655130

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Spesolimab (BI 655130) is a mouse-derived humanized IgG1k antibody against IL-36R. IL-36 plays an important role in the immune system and Spesolimab is being investigated in palmoplantar pustulosis (PPP). Spesolimab was associated with a reduction in biomarkers associated with the innate, Th1/Th17 and neutrophil pathways .
Cat. No.: HY-P991267

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CAN10 is is a humanized monoclonal antibody inhibitor targeting interleukin 1RAP (IL1RAP). CAN10 blocks IL-1, IL-33, and IL-36 signalling by targeting IL1RAP, preventing downstream proinflammatory and profibrotic responses. CAN10 reduces dermal and pulmonary fibrosis. CAN10 can be used for the research of immune system diseases, such as systemic sclerosis .
Cat. No.: HY-P99659
CAS No.: 2102543-86-0
Synonyms: ANB 019

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Imsidolimab (ANB 019) is a high-affinity, humanized monoclonal antibody of anti-IL-36R. Imsidolimab antagonizes IL-36 cytokine signal transduction. Imsidolimab has potential application in generalized pustular psoriasis (GPP) and other inflammatory skin diseases .
Cat. No.: HY-172660
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

36R-D481 is a competitive and orthosteric antagonist of IL-36R, effectively inhibiting IL-36 signaling. 36R-D481 can inhibit IL-36α and IL-36γ but not IL-36β induced IL-8 release .
Cat. No.: HY-P991281

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

REGN6490 is a humanized monoclonal anti-IL1RL2/IL-36R antibody. REGN6490 can be used in research related to pustular psoriasis .
Cat. No.: HY-RS06759
Research Areas:  

Others

IL36A Human Pre-designed siRNA Set A contains three designed siRNAs for IL36A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS20963
Research Areas:  

Others

Il36a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il36a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS06760
Research Areas:  

Others

IL36B Human Pre-designed siRNA Set A contains three designed siRNAs for IL36B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS06761
Research Areas:  

Others

IL36G Human Pre-designed siRNA Set A contains three designed siRNAs for IL36G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS06762
Research Areas:  

Others

IL36RN Human Pre-designed siRNA Set A contains three designed siRNAs for IL36RN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS19695
Research Areas:  

Others

Il36b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il36b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS26190
Research Areas:  

Others

Il36b Rat Pre-designed siRNA Set A contains three designed siRNAs for Il36b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P991468

Target:  

Interleukin Related

Research Areas:  

Cancer

IMM20324 is a human monoclonal antibody (mAb) targeting IL38. IMM20324 inhibits the interaction of IL-38 with human IL1RAPL1-Fc and human IL-36R-Fc with IC50 values of 1.267 nM and 1.4667 nM, respectively. IMM20324 has antitumor activity in the B16.F10 syngeneic mouse model. IMM20324 can be used in antitumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
Cat. No.: HY-P72544
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-36 gamma; IL-36γ; IL36G; IL-1F9; IL-1H1
Species:  
Source:  
Cat. No.: HY-P70670
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL-36 gamma; IL-36γ; Interleukin-36 gamma; IL36G; IL-1-related protein 2; IL-1RP2; IL-1 epsILon; IL-1F9; Interleukin-1 homolog 1; IL-1H1
Species:  
Source:  
Cat. No.: HY-RS27480
Research Areas:  

Others

Il36a Rat Pre-designed siRNA Set A contains three designed siRNAs for Il36a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17831
Research Areas:  

Others

Il36g Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il36g gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS18867
Research Areas:  

Others

Il36rn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il36rn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.