1 Result for "

ILKM-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ILKM-3" in MCE Product Catalog:

Cat. No.: HY-107592
CAS No.: 406208-42-2
Target:  

IKK STAT Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

ACHP (compound 4j) is a selective and orally active IκB kinase inhibitor with IC50 values of 8.5 nM and 250 nM for IKKβ and IKKα, respectively. ACHP can effectively inhibit the STAT3 signaling pathway and induce cancer cell cycle arrest and apoptosis. ACHP shows anti-inflammatory activity in a mouse ear edema model. ACHP can be used in anti-inflammatory and anti-cancer (such as multiple myeloma and leukemia) studies [3] .
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