1 Result for "

INCB191358

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "INCB191358" in MCE Product Catalog:

Cat. No.: HY-183539
CAS No.: 3111036-70-2
Target:  

DGK Interleukin Related

Research Areas:  

Cancer

INCB191358 is a selective and orally active inhibitor of diacylglycerol kinase α/ζ/ι (DGKα/ζ/ι ) with IC50 values of 0.12, 0.36 and 0.36 nM. INCB191358 induces antigen-dependent T-cell activation, induces IL-2 production and enhances antitumor efficacy in combination with PD-1 blockade. INCB191358 can be used for the research of cancer, such as colon carcinoma .
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