1 Result for "

JC-luc cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "JC-luc cells" in MCE Product Catalog:

Cat. No.: HY-161982
CAS No.: 3079468-41-7
Target:  

TNF Receptor

Research Areas:  

Cancer

JNU-0921 is a potent and orally active CD137 agonist. JNU-0921 increases the mRNA expression of IFN-γ and GZMB. JNU-0921 induces luciferase activity with an EC50 value of 64.07 nM.JNU-0921 enhances effector and memory function of cytotoxic CD8 + T cells (CTLs) and alleviates their exhaustion. JNU-0921 also skews polarization of helper T cells toward T helper 1 type and enhances their activity to boost CTL function. JNU-0921 shows anticancer activity .
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