1 Result for "

JMC14

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JMC14" in MCE Product Catalog:

Cat. No.: HY-174366
CAS No.: 2256080-83-6
Target:  

c-Fms PI3K

Research Areas:  

Cancer

JMC14 is a selective and orally active PI3Kδ and CSF1R inhibitor with IC50 values of 12 nM and 143 nM, respectively. JMC14 preferentially inhibits PI3Kδ-mediated signaling at the cellular level. JMC14 demonstrates potent antitumor activity against B-cell lymphomas and triple-negative breast cancer (TNBC) in both in vitro and vivo studies. JMC14 can be used for the study of antitumor immunity .
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