1 Result for "

JMI105

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JMI105" in MCE Product Catalog:

Cat. No.: HY-147849
CAS No.: 2227315-30-0
Target:  

Parasite

Research Areas:  

Infection

JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQ S (3D7; IC50=8.8 µM) and CQ R (RKL-9; IC50=14.3 µM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent .
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