1 Result for "

JNJ 627

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNJ 627" in MCE Product Catalog:

Cat. No.: HY-178714
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .
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