1 Result for "

JNJ28583113

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNJ28583113" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-149143
CAS No.: 2765255-93-2
Purity:  98.82%
Target:  

TRP Channel

Research Areas:  

Inflammation/Immunology

JNJ-28583113 is an TRPM2 antagonist with brain permeability. JNJ-28583113 inhibits TRPM2 blocked phosphorylation of GSK3α and β subunits. JNJ-28583113 protects cells from oxidative stress induced cell death. JNJ-28583113 also suppresses cytokine release in response to pro-inflammatory stimuli in microglia .
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