1 Result for "

JTE151

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JTE151" in MCE Product Catalog:

Cat. No.: HY-155487
CAS No.: 1404380-58-0
JTE-151 is an orally active, selective RORγ antagonist with IC50 values of 20.6 nM, 41.8 nM and 32.2 nM against hRORγ, rRORγ and mRORγ, respectively . JTE-151 reduces the production of IL-17. JTE-151 alleviates paw swelling and bone destruction in arthritis models. JTE-151 can be used in research related to rheumatoid arthritis, collagen-induced arthritis, experimental autoimmune encephalomyelitis, psoriasis, multiple sclerosis and inflammatory bowel disease .
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