1 Result for "

JW-65

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JW-65" in MCE Product Catalog:

Cat. No.: HY-138668
CAS No.: 2763378-71-6
Purity:  99.05%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

JW-65 is a selective TRPC3 channel inhibitor with favorable blood-brain barrier penetration. JW-65 directly binds to human TRPC3 protein and modulates calcium signaling to reduce seizure susceptibility. JW-65 reduces seizure incidence, severity, and duration while prolonging seizure latency in multiple seizure models. JW-65 alleviates Aβ‑induced neuronal damage. JW-65 serves as a valuable tool for research on epilepsy, seizure disorders, and Alzheimer’s disease .
loading...
    loading...