1 Result for "

JW65

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JW65" in MCE Product Catalog:

製品番号: HY-138668
CAS 番号: 2763378-71-6
純度:  99.05%
Target:  

TRP Channel

研究分野:  

Neurological Disease

JW-65 is a selective TRPC3 channel inhibitor with favorable blood-brain barrier penetration. JW-65 directly binds to human TRPC3 protein and modulates calcium signaling to reduce seizure susceptibility. JW-65 reduces seizure incidence, severity, and duration while prolonging seizure latency in multiple seizure models. JW-65 alleviates Aβ‑induced neuronal damage. JW-65 serves as a valuable tool for research on epilepsy, seizure disorders, and Alzheimer’s disease .
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