3 Results for "

JZL195

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "JZL195" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-15250
CAS No.: 1210004-12-8
Purity:  99.75%
Target:  

FAAH MAGL Autophagy

Research Areas:  

Neurological Disease

JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively .
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Cat. No.: HY-15250R
CAS No.: 1210004-12-8
Target:  

FAAH MAGL Autophagy

Research Areas:  

Neurological Disease

JZL195 (Standard) is the analytical standard of JZL195. This product is intended for research and analytical applications. JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively .
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Cat. No.: HY-W770198
Synonyms: 2-Monolinolein-d5; 2-Monolinoleoylglycerol-d5
2-Linoleoyl glycerol-d5 (2-Monolinolein-d5; 2-Monolinoleoylglycerol-d5) is the deuterium labeled 2-Linoleoyl glycerol (HY-130311). 2-Linoleoyl glycerol (2-Monolinolein; 2-Monolinoleoylglycerol) is a monoacylglycerol that is an antagonist and partial agonist at the type 1 cannabinoid CB1 receptor. The potency of 2-Linoleoyl glycerol can be enhanced by JZL195 (HY-15250), an inhibitor of FAAH and MAGL, and inhibited by the CB1 antagonist AM251 (HY-15443) and Cannabidiol. As a CB1 antagonist, 2-Linoleoyl glycerol does not enhance, but only attenuates, the activity of the CB1/CB2 receptor ligands cannabinoids (AEA) and 2-arachidonoylglycerol (2-AG) .
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