1 Result for "

KAI-11101

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KAI-11101" in MCE Product Catalog:

Cat. No.: HY-170484
Target:  

MAP3K p38 MAPK

Research Areas:  

Neurological Disease

KAI-11101 is the inhibitor for dual leucine zipper kinase (DLK, MAP3K12) with a Ki of 0.7 nM. KAI-11101 inhibits Paclitaxel (HY-B0015)-induced cJun phosphorylation (IC50=95 nM) and thus inhibits the activation of MAPK pathway. KAI-11101 is blood brain barrier penetrable and can be further investigated for its neuroprotective property .
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