1 Result for "

KN046

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "KN046" in MCE Product Catalog:

Cat. No.: HY-P99943
CAS No.: 2367013-69-0
Synonyms: KN-046

Target:  

PD-1/PD-L1 CTLA-4

Research Areas:  

Cancer

Erfonrilimab (KN-046) is a monoclonal antibody targeting PD-L1/CTLA-4. Erfonrilimab blocks the PD-L1 and CTLA-4 pathways, thereby regulating T cell function. Erfonrilimab enhances the secretion of IL-2 in superantigen-stimulated peripheral blood mononuclear cells. Erfonrilimab inhibits tumor growth in xenograft and double gene knock-in mouse models. Erfonrilimab can be used in research related to a variety of advanced solid tumors, including non-small cell lung cancer and nasopharyngeal carcinoma.
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