1 Result for "

KSP-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "KSP-5" in MCE Product Catalog:

Cat. No.: HY-177285
CAS No.: 1161925-41-2
Target:  

Kinesin ADC Payloads

Research Areas:  

Cancer

NVP-BQS481 (Compound 1) is a selective Kinesin spindle protein-5 (Eg5) inhibitor with an IC50< 0.5 nM. NVP-BQS481 has significant antimitotic and antitumor activity (IC50: 0.0.9 nM for SK-OV-3ip cells). NVP-BQS481 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
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