1 Result for "

KT-5720

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KT-5720" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N6789
CAS No.: 108068-98-0
Target:  

PKA

Research Areas:  

Neurological Disease Cancer

KT5720 is a potent, cell-permeable, specific, reversible and ATP-competitive PKA inhibitor (IC50=3.3 μM). KT5720 is effective in reversing MDR1-mediated multidrug resistance. KT5720 also reduces the excitability of dorsal root ganglion (DRG) neurons by attenuating Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity and reducing intracellular Ca2 + concentrations. KT5720 can be used in the study of haematological malignancies as well as HCN and DRG neuron-related diseases .
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