1 Result for "

KY 19382

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KY 19382" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-131447
CAS No.: 2226664-93-1
Purity:  ≥98.0%
Synonyms: A3051
Target:  

GSK-3 Wnt β-catenin

Research Areas:  

Metabolic Disease

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases .
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