1 Result for "

Kelly WT cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Kelly WT cells" in MCE Product Catalog:

Cat. No.: HY-180907
Target:  

PROTACs Deubiquitinase

Research Areas:  

Cancer

PROTAC USP39 Degrader-1 is a USP39 PROTAC degrader with Kd values of 136 nM and 232 nM, and a DC50 value of 1.06 nM (24 h). PROTAC USP39 Degrader-1 binds to the VHL E3 ubiquitin ligase, forms a ternary complex with USP39, mediates USP39 ubiquitination and proteasomal degradation dependent on VHL recruitment, modulates splicing activity and induces 5' splice site-specific splicing patterns. PROTAC USP39 Degrader-1 can be used in the research of cervical cancer .
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