1 Result for "

L162782

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "L162782" in MCE Product Catalog:

Cat. No.: HY-125094
CAS No.: 169281-92-9
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

L-162782 is a high affinity AT1 receptor ligand for rat and human wild-type AT1 with IC50 values of 28.5 and 24.6 nM, respectively. L-162782 acts as a partial agonist (EC50 ≈ 30 nM) and insurmountable antagonist (IC50 = 6.5 μM) on wild-type rat AT1 receptors in COS-7 cells. L-162782 reduces Angiotensin II (HY-13948)-induced phosphatidylinositol turnover. L-162782 can be used for hypertension research .
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