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LDHA-IN-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100742
    GNE-140 racemate
    5+ Cited Publications

    		 Lactate Dehydrogenase Cancer
    GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor .
    GNE-140 racemate
  • HY-16964
    LDHA-IN-1

    		Lactate Dehydrogenase Cancer
    LDHA-IN-1 (Compound 1j) is a selective, competitive LDH-A inhibitor, with Ki values of 8.9 μM (NADH assay) and 4.7 μM (Pyruvate assay) against hLDH-A. LDHA-IN-1 inhibits cancer cell proliferation under hypoxic conditions. LDHA-IN-1 can be used in the research of ovarian cancer, colorectal cancer, mesothelioma and pancreatic cancer [1].
    LDHA-IN-1
  • HY-180992
    Dual GO/LDHA-IN-1

    		Lactate Dehydrogenase Metabolic Disease
    Dual GO/LDHA-IN-1 is an orally available dual inhibitor targeting glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), with Ki values of 390 nM and 40 nM, respectively. Dual GO/LDHA-IN-1 reduces hepatic LDHA levels, urinary oxalate excretion, and renal calcium-oxalate crystal deposition. Dual GO/LDHA-IN-1 is applicable for research on primary hyperoxaluria type 1 [1].
    Dual GO/LDHA-IN-1
  • HY-100742R
    GNE-140 racemate (Standard)

    		Lactate Dehydrogenase Reference Standards Cancer
    GNE-140 (racemate) (Standard) is the analytical standard of GNE-140 (racemate) (HY-100742). This product is intended for research and analytical applications. GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor .
    GNE-140 racemate (Standard)

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