1 Result for "

LIBX-A401

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LIBX-A401" in MCE Product Catalog:

Cat. No.: HY-173432
CAS No.: 3111845-07-6
Target:  

ACSL Family Ferroptosis

Research Areas:  

Neurological Disease Cancer

LIBX-A401 is a selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor with a human IC50 values of 0.38 μM and a Kd of 0.72 μM. LIBX-A401 binds to ACSL4 in an ATP-dependent manner, stabilizes the C-terminal domain, alters the fatty acid gate region, and interacts with residues A329 and Q302 within the fatty acid binding site. LIBX-A401 exhibits anti-ferroptosis properties in cells. LIBX-A401 can be used for the researches of cancer and parkinson's disease .
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