1 Result for "

LIN28-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LIN28-IN-1" in MCE Product Catalog:

Cat. No.: HY-155237
Target:  

MicroRNA

Research Areas:  

Cancer

LIN28-IN-1 (compound 5) is an inhibitor of the RNA-binding and regulatory protein LIN28 and binds to the LIN28 cold shock domain (CSD). LIN28-IN-1 effectively inhibits the interaction between LIN28 and let-7 miRNA (IC50: 5.4 μM), blocking the negative impact of LIN28 on epigenetic gene regulation. LIN28-IN-1 significantly inhibits the proliferation of JAR cancer cells expressing LIN28 (IC50: 6.4 μM) .
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