2 Results for "

LM305

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LM305" in MCE Product Catalog:

Cat. No.: HY-P991197
Synonyms: LM-305 antibody; AZD-0305 antibody

Target:  

CD3

Research Areas:  

Cancer

Anti-GPRC5D Antibody (LM-305 antibody) is a humanized IgG1 monoclonal antibody that targets GPRC5D. Anti-GPRC5D Antibody is the antibody part of the ADC molecule LM-305. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-171754
Research Areas:  

Cancer

LM-305 is an anti-G protein-coupled receptor class 5 member D (GPRC5D) antibody-drug conjugate (ADC). LM-305 consists of Anti-GPRC5D Antibody (HY-P991197) and VcMMAE (HY-15575). LM-305 exhibits potent cytotoxicity against multiple myeloma cells (NCI-H929 and MM.1R) with IC50 values ranging from 0.1 to 0.3 nM. LM-305 can be used in the study of GPRC5D-related relapsed and refractory multiple myeloma (RRMM) .
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