1 Result for "

LPM 4870108

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LPM 4870108" in MCE Product Catalog:

Cat. No.: HY-132229
CAS No.: 2803679-07-2
Target:  

Trk Receptor

Research Areas:  

Cancer

LPM4870108 is a potent and orally active pan-Trk (WT and MT) inhibitor, with IC50s of 0.2 nM, 2.4 nM, 3.5 nM and 2.3 nM for TrkC, TrkA, TrkA G595R and TrkA G667C, respectively. LPM4870108 shows selectivity for Trk over ALK (IC50=182 nM). LPM4870108 exhibits anti-tumor activity .
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