1 Result for "

LR1143

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LR1143" in MCE Product Catalog:

Cat. No.: HY-124186
CAS No.: 150151-15-8
Research Areas:  

Neurological Disease

LR1143 is a dopamine transporter (DAT) and 5-HT uptake inhibitor, with IC50 values of 3.4 nM and 112 nM in rats, respectively. LR1143 binds to DAT labeled with the dopamine reuptake inhibitor GBR 12935 (HY-12242A), with an IC50 of 4.4 nM. LR1143 shows lower selectivity for DAT than for serotonin reuptake sites. LR1143 can be used in studies related to cocaine abuse .
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