1 Result for "

LYG409

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LYG409" in MCE Product Catalog:

Cat. No.: HY-170952
CAS No.: 3053857-55-6
Target:  

Molecular Glues

Research Areas:  

Cancer

LYG-409 is an orally active degrader of GSPT1. LYG-409 shows excellent anti-acute myeloid leukemia and prostate cancer in vivo with TGI of 94.34% and 104.49%, respectively. LYG-409 inhibits KG-1 cells mediated by the degradation of GSPT1 with an IC50 of 9.50 nM, with a DC50 of 7.87 nM in vitro .
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