2 Results for "

Lipid114

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Lipid114" in MCE Product Catalog:

Cat. No.: HY-171900
Target:  

Liposome

Research Areas:  

Inflammation/Immunology

Lipid 114 is an ionizable cationic lipid with a pKa of approximately 6.8. Lipid 114 can be used to generate lipid nanoparticles (LNP) to deliver siRNA in vitro as well as in vivo. Lipid 114 LNPs encapsulating siRNA that targets IL-1β can reduce IL-1β expression in macrophages. Lipid 114 LNPs encapsulating siRNA that targets IL-1β also reduces hepatic and renal expression of IL-1β, as well as decreasing hepatic inflammation in mouse model with LPS-induced acute liver failure .
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Cat. No.: HY-175148
Research Areas:  

Others

Hexa lipid 114 is an ionizable cationic lipid and a derivative of lipid 114 (HY-171900).
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