1 Result for "

M2 L27F

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "M2 L27F" in MCE Product Catalog:

Cat. No.: HY-175804
CAS No.: 2260797-32-6
Target:  

SARS-CoV

Research Areas:  

Infection

M2 ion channel blocker-2 (Compound 10) is a M2 channel blocker. M2 ion channel blocker-2 significantly blocks wild-type and mutant M2 (L27F and V27A) ion channels. M2 ion channel blocker-2 has potent antiviral activity against HCoV-229E (EC50: 4.7  μM in cytopathic effect) but not against influenza A virus. M2 ion channel blocker-2 has no significant inhibition of hERG and cytochrome P450 (CYP1A2, CYP2C19, and CYP3A4) activity .
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