1 Result for "

M3686

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "M3686" in MCE Product Catalog:

Cat. No.: HY-170764
CAS No.: 2738550-24-6
Target:  

YAP

Research Areas:  

Cancer

M3686 (Compound 29) is a potent, selective TEAD1 inhibitor with an IC50 value of 51 nM. M3686 also shows weaker binding activity on TEAD3. M3686 potently inhibits cell viability against YAP-dependent NCI-H226 cell line with an IC50 value of 0.06 uM. M3686 shows strong anti-tumor effects in the NCI-H226 xenograft model .
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