1 Result for "

MDR-positive

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MDR-positive" in MCE Product Catalog:

Cat. No.: HY-116852
CAS No.: 2730-71-4
Purity:  99.77%
Research Areas:  

Cancer

Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis . Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
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