1 Result for "

MEDI3622

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MEDI3622" in MCE Product Catalog:

Cat. No.: HY-P992406

Target:  

MMP IFNAR

Research Areas:  

Cancer

MEDI-3622 is a human monoclonal antibody against ADAM17. MEDI-3622 blocks the ADAM17-mediated shedding of CD16A and CD62L on NK cells, and binds with high specificity to a surface loop unique to the metalloprotease catalytic domain of ADAM17. MEDI-3622 enhances IFNγ production by NK cells when they bind to antibody-coated tumor cells. MEDI-3622 can be used in the research of ovarian cancer, Burkitt lymphoma, head and neck cancer, and colorectal cancer .
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