1 Result for "

MEL-23

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MEL-23" in MCE Product Catalog:

Cat. No.: HY-148106
CAS No.: 642072-49-9
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

MEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription .
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