1 Result for "

MEN1112

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MEN1112" in MCE Product Catalog:

Cat. No.: HY-P991665
Synonyms: OBT357NF; OBT357

Research Areas:  

Cancer

MEN1112 (OBT357NF; OBT357) is a defucosylated humanized monoclonal antibody targeting Bst1/CD157, with an EC50 of 0.4 nM. MEN1112 binds to Bst1/CD157 on acute myeloid leukemia cells, triggers slow antigen internalization, induces antibody-dependent cell-mediated cytotoxicity, and mediates the lysis of acute myeloid leukemia cells and blasts. MEN1112 is applicable for research related to acute myeloid leukemia .
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