1 Result for "

MM927

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MM927" in MCE Product Catalog:

Cat. No.: HY-175783
CAS No.: 3065567-21-4
Target:  

Apoptosis

Research Areas:  

Cancer

MM927 is a potent NVL inhibitor, with an IC50 of 0.053 μM. MM927 blocks 60S ribosomal subunit biogenesis in the nucleolus. MM927 induces half-mer polysomes, cell cycle arrest at G1/S and G2/M and apoptosis in cells. MM927 demonstrates antitumor efficacy in MOLM-13 AML and HCT116 CRC xenograft models. MM927 can be used for the study of cancers such as acute myeloid leukemia (AML) and colorectal cancer (CRC) .
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