2 Results for "

MO7e cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MO7e cells" in MCE Product Catalog:

Cat. No.: HY-177286
CAS No.: 1185279-55-3
Target:  

c-Kit

Research Areas:  

Inflammation/Immunology Cancer

c-Kit-IN-11 (Compound A7) is a c-Kit inhibitor with an IC50 of 76  nM for Mo7e cells. c-Kit-IN-11 can be used for inflammatory like asthma and malignant cancers research .
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Cat. No.: HY-135435
CAS No.: 515821-11-1
Target:  

VEGFR PDGFR FGFR

SU10944 is a selective, orally active VEGFR inhibitor, with an IC50 of 6 nM against VEGFR-1, an IC50 of 96 nM and a Ki of 21 nM against VEGFR-2. SU10944 only exhibits weak inhibitory activity against PDGFRβ (IC50 = 1 μM), SCFR (IC50 = 1.58 μM) and FGFR-1 (IC50 = 1.6 μM). SU10944 selectively inhibits VEGFR receptor downstream signaling, neovascularization, vascular permeability, VEGF-mediated tissue factor production, and induces tumor growth delay. SU10944 can be used in research related to diabetic retinopathy, exudative age-related macular degeneration or cancer .
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