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Cat. No.: HY-177286

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c-Kit-IN-11

c-Kit-IN-11 (Compound A7) is a c-Kit inhibitor with an IC₅₀ of 76  nM for Mo7e cells. c-Kit-IN-11 can be used for inflammatory like asthma and malignant cancers research.

For research use only. We do not sell to patients.

CAS No.: 1185279-55-3
Formula: C₂₅H₂₁N₅O₂
Molecular Weight:423.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

c-Kit-IN-11 Chemical Structure

CAS No.: 1185279-55-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

c-Kit-IN-11 (Compound A7) is a c-Kit inhibitor with an IC₅₀ of 76  nM for Mo7e cells. c-Kit-IN-11 can be used for inflammatory like asthma and malignant cancers research^[1].

Chemical Information

CAS No. 1185279-55-3
Molecular Weight 423.47
Formula C₂₅H₂₁N₅O₂
SMILES

O=C1C(C2=CC(NC3=NOC(C4=CC=CC=C4)=N3)=CC=C2C)=CC5=C(N1C)C=C(C)N=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li X L, et al. Heterocyclic compounds and compositions as c-kit and pdgfr kinase inhibitors. WO2009105712A1. 2009-08-27.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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