1 Result for "

MPP+-d3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MPP+-d3" in MCE Product Catalog:

Cat. No.: HY-W008719S
CAS No.: 207556-07-8
MPP+-d3 (iodide) is deuterium labeled MPP+ (iodide). MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT) .
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