1 Result for "

MSU44147

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MSU44147" in MCE Product Catalog:

Cat. No.: HY-181282
CAS No.: 3105177-29-2
Target:  

Bacterial

Research Areas:  

Infection

MSU-44147 is an inhibitor and antimicrobial agent targeting MmpL3 in Mycobacterium abscessus, with low eukaryotic cytotoxicity, a narrow antimicrobial spectrum that is specific only to mycobacteria, and low drug resistance frequency. MSU-44147 reduces trehalose dimycolate levels by inhibiting MmpL3 function, disrupts biofilm formation and reduces the viability of related bacteria, while exerting bactericidal effects on intracellular Mycobacterium abscessus. MSU-44147 exhibits additive or synergistic effects with antibiotics and can be used in research on multidrug-resistant isolates and infections of Mycobacterium abscessus .
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