1 Result for "

MV-14

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MV-14" in MCE Product Catalog:

Cat. No.: HY-144777
CAS No.: 2620551-45-1
Target:  

FLT3 Apoptosis

Research Areas:  

Cancer

FLT3-IN-14 is a potent FLT3 inhibitor with IC50s of 5.6 nM and 1.4 nM for FLT3-WT and FLT3-ITD. FLT3-IN-14 reduces the phosphorylation of FLT3 (Y591), induces cell cycle arrest at G1 phase and apoptosis. FLT3-IN-14 significantly reduces the tumor growth in an MV4-11 xenograft mouse model .
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